Safety of metformin use during the first trimester.
نویسندگان
چکیده
منابع مشابه
First-trimester exposure to metformin and risk of birth defects: a systematic review and meta-analysis.
BACKGROUND Metformin is generally considered a non-teratogenic drug; however, only a few studies specifically designed to assess the rate of congenital anomalies after metformin use have been published in the literature. The objects of the present study were to review all of the prospective and retrospective studies reporting on women treated with metformin at least during the first trimester o...
متن کاملPregnancy outcomes among women with polycystic ovary syndrome treated with metformin.
BACKGROUND We sought to determine whether metformin, which had facilitated conception in 72 oligoamenorrhoeic women with polycystic ovary syndrome (PCOS), would safely reduce the rate of first trimester spontaneous abortion (SAB) and increase the number of live births without teratogenicity. METHODS Seventy-two oligoamenorrheic women with PCOS conceived on metformin (2.55 g/day). They were pr...
متن کاملResponse to Comment on Nachum et al. Glyburide Versus Metformin and Their Combination for the Treatment of Gestational Diabetes Mellitus: A Randomized Controlled Study. Diabetes Care 2017;40:332-337.
The comment by Barbour and Davies (1) acknowledges that our study (2) is important given the increasing popularity of oral agents to treat gestational diabetes mellitus (GDM)but raises concernswhether the study design and conclusions can be generalized to other GDM populations. With regard to treatment efficacy before 24 weeks, in our study the success rate of oral treatments before and after 2...
متن کاملO-37: Yolk Sac Diameter and Embryonic Heart Rate As Prognostic Factors of First Trimester Spontaneous Miscarriage
Background: During the past 20 years a lot of information is achieved about the first trimester of pregnancy through ultrasound and intrauterine fertilization. Many researchers tried to use the symptoms of ultrasound in early pregnancy like measuring the gestational sac and yolk sac of the pregnancy to predict the continuation of pregnancy. Aim of the recent study is to predict the risk of spon...
متن کاملبررسی الگوی مصرف دارو باتوجه به کاتگوری تعیین شده توسط FDA در زنان باردارمراجعه کننده به مراکز بهداشتی – درمانی شهر همدان
Introduction & Objective:The use of medications during pregnancy poses a potential risk to both mother and the fetus. FDA classifies various drugs used in pregnancy, and provides therapeutic guidance for the clinician .The purpose of this study was to determine the pattern of drug consumption during pregnancy. Materials & Methods: This descriptive-analytic study was performed using questionnai...
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عنوان ژورنال:
- Canadian family physician Medecin de famille canadien
دوره 51 شماره
صفحات -
تاریخ انتشار 2005